MIMIC: A Multi-centre Cohort Study Evaluating the role of Inflammatory Markers in Patient’s Presenting with Acute Ureteric Colic

 Service Evaluation Project 

A multi-centre service evaluation of the management of patients presenting with acute ureteric Colic (MIMIC)


Admission to A&E is very common with over 750,000 patients admitted every year in the EU. Current practice in admitting and managing this condition is not clearly known.

Aim and Objective

We would like to assess the intervention rates of patients who are admitted with acute ureteric colic and assess which tests are commonly done in their work up. Of interest is what role clinicians give to inflammatory markers in their management of patients and what imaging tests and interventions were carried out.


Multi-centre national service evaluation in a 1000 patients who have previously been admitted with acute ureteric colic will have data recorded of the date of their first CT scan, the admission details including blood test results and follow up details including whether intervention or imaging was carried out. This is to be collected for patients who have already been managed by their hospital team and whose details are already stored in the trust imaging system and electronic records.

The project meets the criteria for as a service evaluation project as per the HRA online tool (see attachment below) and has also been evaluated by the R&D department at University College London Hospital and deemed as non-research.

This service evaluation will be carried out at a number of hospital sites. It is hoped that observing intervention practice and looking at variation in practice between sites may help us identify areas for service improvement.

Local Hospital Trust data management policies will be followed. No patient identifiable data will leave the original site. If any communications containing patient identifiable information are deemed necessary they will only be conducted via nhs.net email accounts or Trust email accounts.

Primary Objective
  • To examine whether or not there is any evidence of regional variation within the UK in the proportion of acute ureteric colic patients who undergo intervention.
Secondary Objectives 
  • To determine the level of association, if any, between white blood cell count (WBC count) and subsequent intervention in patients who present with acute ureteric colic.
Deliverables for Audit Departments

In patients admitted with ureteric colic:
  • Intervention rate
  • Intervention type
  • Timing
  • Inflammatory marker levels at presentation
Pilot has been completed
Approved by 6 Audit Departments and carried out in 120 Patients from 6 UK Centers
  • Taimur Shah                     Whittington Hospital, London
  • Veeru Kasivisvanathan     University College Hospital, London
  • Ben Lamb                          University College Hospital, London
  • Sophia Cashman               Peterborough City Hospital, Cambridgeshire
  • Karl Pang                           Sheffield Teaching Hospitals, Sheffield
  • Marcus Cumberbatch       Sheffield Teaching Hospitals, Sheffield
  • Arjun Nambiar                  Cumberland Infirmary, Cumbria
  • James Akman                   St Bartholemew’s Hospital, London

MIMIC Poster

EAU MIMIC Poster 190217

MIMIC Achievements

MIMIC Sneak PeakTaimur Shah – Lead of MIMIC and Won Best Poster in session at EAU 2017
Chuanyu SURG
Chuanyu Gao – Won Best Presentation at SURG 2017
Image uploaded from iOS
Kevin Gallagher – runner up for BJS/ASiT methodology prize, Nov 2017
Taimur Shah – won best in session at EAU 2018, Copenhagen, March 2018

List of MIMIC Achievements

Date Type Achievement Evidence
April 2018 Prize Best ePoster, BAUS 2018, Liverpool, UK Link
April 2018 Prize ASIT/SARS Winner 2018, Edinburgh, UK Link
March 2018 Prize Best in Session at European Association of Urology (EAU) 2018 Annual Meeting, Copenhagen, Denmark Link
March 2018 Poster Presentation European Association of Urology (EAU) 2018 Annual Meeting, Copenhagen, Denmark Link
October 2017 Publication MIMIC Study Protocol Published in International Journal of Surgery Protocols Link

Cite as: A multi-centre cohort study evaluating the role of inflammatory markers in patient’s presenting with acute ureteric colic (MIMIC) (2017) T. Shah et al. International Journal of Surgery Protocols 6 (2017) 1–4.

November 2017 Prize Runner up for BJS/ASiT Methodology Prize, at National Research Collaborative Meeting 2017, Birmingham N/A
July 2017 Prize Best Presentation at Specialist Urology Registrars’ Group 2017 Annual Meeting Link
April 2017 Prize Best National Research Collaborative Prize – Birmingham Surgical Trials Consortium Prize (BiSTC) at ASIT Conference 2017, Bournemouth, UK Link
March 2017 Prize Best in Session at European Association of Urology (EAU) 2017 Annual Meeting, London, UK Link
October 2017 Oral Presentation National Research Collaborative Meeting 2017, Birmingham N/A
October 2017 Poster Presentations Society of International Urology (SIU) 2017 Annual Meeting, Lisbon, Portugal Link
September 2017 Oral Presentations Irish Society of Urology (ISU) 2017, Cork, Ireland Link
September 2017 Oral Presentation World Congress of Endourology (WCE) 2017, Vancouver, Canada Link
July 2017 Oral Presentation Specialist Urology Registrars’ Group 2017 Annual Meeting Link
May 2017 Poster Presentation 7th International Meeting Challenges in Endourology, Paris, France Link
April 2017 Oral Presentation ASIT Conference 2017, Bournemouth, UK Link
March 2017 Poster Presentation European Association of Urology (EAU) 2017 Annual Meeting, London, UK Abstract


Download all evidence here

MIMIC Collaborators

Evidence for all collaborators

List of MIMIC Collaborators

Hospital Collaborators
Addenbrooke’s Hospital Nicholas Ivin, Jonathan Maw, Ali Abdaal, Cissy
Austin Hospital, Heidelberg, Victoria, Australia Todd Manning, Daniel Christidis
Barts Health, Whipps Cross and the Royal London Shahid Khan, Sibel Demirel
Bendigo Health, Australia Samantha Koschel, Henry Badgery
Box Hill Hospital, Melbourne, Australia Luke Luoke Wang, Tatenda Calvin Nzenza
Broomfield Hospital Ruzi Begum, Shazia Hamad, Aarti Shetty
Charing Cross Hospital Hamid Abboudi, Rozh Jalil
Cheltenham General Hospital Cherrie Wing Yin Ho, Iram Parwaiz
Chester Hospital, Mersey Fraser Cameron, Connie Shingles
Craigavon Area Hospital, Northern Ireland Jessica S. Morrow, David Curry
Cumberland Infirmary Carlisle Kenneth Russell MacKenzie, Kyle Reid
Darent Valley Hospital Nazrin Assaf, Adekinte Oyekan
Dorset County Hospital, Dorchester Zara Hayat , Victoria Morrison-Jones
Edinburgh Alexander Laird, Abhishek D Sharma
Fiona Stanley Hospital, Perth, Western Australia Simeon Ngweso, Munyaradzi Nyandoro
Forth Valley Royal hospital Jane Hendry, Lynne Kerr
Freeman hospital, newcastle Andrew Harris
Glasgow Royal Infirmary Flora Rodger, Emma Docherty, Guat Shi Ng
Great Western Hospital, Swindon Haitham Abdelmoteleb
Guys Hospital David Eldred-Evans
Harlow Hospital, Princess Alexandra Hospital Thomas Stonier, Nick Simson, Harpreet Kaur Sekhon Inderjit SIngh, Emer Hatem
Heart of England NHS FT (Birmingham) Rebecca Tregunna
Heidelberg Repatriation Hospital, Australia Shannon McGrath, Jonathan O’Brien
High Wycombe Hospital Angus Campbell, Peter Linton Cronbach
James Cook University Hospital, Middlesborough Arjun Nambier, Campbell D Tait
James Paget University Hospital, Great Yarmouth Lokesh Suraparaju, James W O’Brien
Kettering General Hospital Rahul Pankhania
King’s College Hospital Robert Foley, Abisoye Akintimehin
Kingston Hospital Monika Rezacova, Eric Edison
Lister hospital, Stevenage Florence Kashora, Osayuki Nehikhare, Nadine McCauley
Luton and Dunstable hospital Kishan Tailor
Manchester Royal Infirmary Angus Chin On Luk
Maroondah Hospital, Eastern Health Christopher Steen, Matthew Alberto
Musgrove Park Hospital Taunton James Olivier, Joel Tay
Norfolk and Norwich Jack Coode-Bate, Madhavi Natarajan
North Manchester General Hospital James Akman
Northampton General Hospital Kevin Murtagh, Anne Carrie
Northwick Park / Central Middlesex Nishant Bedi
Nottingham Univeristy Hospitals Manar Malki, Frances Burge
Peterborough City Hospital Iannish Sadien, Iqbal Miakhil
Princess Royal Hospital Haywards Heath Patrick Olaniyi, Roelof Joe Stammeijer, Hannah Mason
Queen Alexandra Hospital, Portsmouth Lisa Lavan
Queen Elizabeth Hospital, Birmingham Carol Wong, Sarah Al-Shakhshir
Queen Elizabeth Hospital, Kings Lynn Wesam Al-Dhahir, Mohamed Ahmed Abdelhafiz Abu Yousif,
Rotherham general hospital Li June Tay, A. E. Ward
Royal Alexandria Hospital, Paisley, Scotland Alastair Crawford McKay
Royal Devon and Exeter hospital L.A.M Simmons, S Khadhouri
Royal Free Hospital John Withington
Royal United Hospitals Bath Jonathan Lee Chuo Min
Salford Matthew Liew, Richard Simpson
Sheffield Marcus G Cumberbatch, Karl H Pang
Southend University Hospital Robert Adams, Asfand Baig Mirza
Southmead Hospital/Severn Deanery Johnson Pok-Him Tam, Edward Tudor
St George’s Hospital, London Michael Gallagher, Yaamini Premakumar, Michael Ager
St James’s University Hospital, Leeds Andrei Adrian Kozan, Ata Jaffer, Waqas Din
St Vincent’s University Hospital in Dublin, Ireland Mudit Matanhelia,  Stephen Moyles
Sunderland Daniel Ness
Torbay and Devon Kellie Bateman
Ulster Hospital, Belfast, Northern Ireland Joshua Michael Clements, Gemma Hann, Catherine Gilmore
University College London Hospital Ben Lamb, Gidon Ellis, Chuanyu Gao
University Hospital of South Manchester Laura Derbyshire
Unversity Hospital Wales Rebecca Mosey, Banan Osman
Wellington Hospital, New Zealand Omid Yassaie, George Weeratunga
Western Heatlh Australia Cristian Udovicich
Weston Super Mare Su-Min Lee, Ali Hussain
Whiston Hospital, Merseyside James Mbuvi, Heather Stewart
Whittington Hospital Taimur Shah, Archie Hughes-Hallet
Wigan Infirmary Sean AF Rezvani , Shawn Ooi Peng Sheng
Worthing Hospital, Western Sussex NHS Trust Francesca Kum, Rebecca Symes
Wrexham Maelor Hospital Issam Ahmed